Abstract |
We report the case of a 76-year-old woman who presented with asymptomatic extensive erythematous. Firm plaques were noted over the right cheek. Complete blood count was normal, as was a peripheral smear. An excision biopsy taken from the cheek showed infiltration of the dermis and hypodermis with atypical cells which were strongly positive for human leukocyte antigen ( HLA-DR) and lysozyme and were moderately myeloperoxidase (MPO) enzyme. The results of immunohistochemical staining for CD34, CD117, CD3, CD4, CD8, CD20, CD23, CD56, and ALK-1 were negative. Bone marrow analysis indicated myelodysplastic syndrome RAEB 1 while cytogenetic finding showed tetrasomy 8. It was recommended that the patient undergo local radiotherapy of skin lesions, but she refused and was lost to follow-up.
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Authors | Darko Antic, Andrija Bogdanovic, Maja Perunicic Jovanovic, Jelica Jovanovic, Ivo Elezovic |
Journal | Acta dermatovenerologica Croatica : ADC
(Acta Dermatovenerol Croat)
Vol. 23
Issue 2
Pg. 134-7
( 2015)
ISSN: 1847-6538 [Electronic] Croatia |
PMID | 26228825
(Publication Type: Case Reports, Journal Article)
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Topics |
- Aged
- Biopsy, Needle
- Female
- Humans
- Immunohistochemistry
- Myelodysplastic Syndromes
(complications, pathology, physiopathology)
- Neoplasm Invasiveness
(pathology)
- Neoplasm Staging
- Prognosis
- Risk Assessment
- Sarcoma, Myeloid
(complications, pathology, physiopathology)
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