HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis.

AbstractPURPOSE:
Chronic tendinopathy of lateral epicondyle of the humerus, commonly known as "tennis elbow" is one of the most frequent tendinopathies caused by recurrent overload of the muscle origins. The aim of the study was to assess the effectiveness of treating lateral epicondylitis (LE) with autologous conditioned plasma (ACP) and betamethasone injections, and to compare these methods over the course of a one year follow-up.
METHODS:
Patients were randomly placed into one of into two groups: 53 were treated with ACP, and 46 with 1 ml betamethasone injections and 2 ml of 1 % lignocaine. Both those groups were comparable in terms of initial DASH score.
RESULTS:
After six weeks and six months, the mean DASH score was significantly better in the betamethasone group, but was better in ACP group after one year. Full recovery (patients with no symptoms) at all time points was more common in the betamethasone group. A comparison of grouped DASH scores revealed more very good and good results in the ACP group after one year. More patients had pain symptoms related to injection in the ACP group than the betamethasone group.
CONCLUSIONS:
ACP therapy of LE allows better results to be obtained at 12 months. Betamethasone injections give more rapid improvement, but the therapeutic effect is longer lasting in the ACP group.
AuthorsRadosław Lebiedziński, Marek Synder, Piotr Buchcic, Michał Polguj, Andrzej Grzegorzewski, Marcin Sibiński
JournalInternational orthopaedics (Int Orthop) Vol. 39 Issue 11 Pg. 2199-203 (Nov 2015) ISSN: 1432-5195 [Electronic] Germany
PMID26224613 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Glucocorticoids
  • Betamethasone
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Betamethasone (administration & dosage)
  • Female
  • Follow-Up Studies
  • Glucocorticoids (administration & dosage)
  • Humans
  • Injections
  • Male
  • Middle Aged
  • Pain Measurement
  • Platelet-Rich Plasma
  • Prospective Studies
  • Tennis Elbow (therapy)
  • Transplantation, Autologous
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: