Effect of Cranial Window Diameter During Deep Brain Stimulation Surgery on Volume of Pneumocephalus.

Successful deep brain stimulation (DBS) surgery necessitates high accuracy in targeting specific intracranial nuclei. Brain shift due to pneumocephalus can contribute to decreased accuracy. Larger burr holes and dural openings may increase pneumocephalus volume due to a greater degree of communication between the subdural space and extracranial air. The aim of this study is to determine if there is a statistically and clinically significant difference in postoperative pneumocephalus volume related to burr hole and durotomy size.
DBS electrodes were surgically implanted through either large (14 mm) burr holes or small (4 mm) twist drill holes. Immediate postoperative computerized tomography (CT) scans of 165 electrode implantations in 85 patients from 2010 to 2013 were retrospectively analyzed. Student's t-test and Mann-Whitney U-test were employed with a threshold of significance set at p ≤ 0.05.
No significant difference in pneumocephalus was identified between patients who had implantation of DBS electrodes through 4 mm twist drill holes (N = 71 hemispheres, 12.84 ± 9.79 cm(3) ) and those with large 14 mm burr holes (N = 87, 11.70 ± 7.46 cm(3) , p = 0.42). Volume of pneumocephalus did not correlate with duration of surgery or patient age. The groups did not differ significantly with respect to other aspects of surgical implantation technique or surgical duration.
While identifying factors that may reduce pneumocephalus volume may be critical to improving stereotactic accuracy and targeting, the current results suggest that burr hole size may not alter the degree of brain shift.
AuthorsJustin Sharim, Patrick Pezeshkian, Antonio DeSalles, Nader Pouratian
JournalNeuromodulation : journal of the International Neuromodulation Society (Neuromodulation) Vol. 18 Issue 7 Pg. 574-9 (Oct 2015) ISSN: 1525-1403 [Electronic] United States
PMID26222380 (Publication Type: Journal Article)
Copyright© 2015 International Neuromodulation Society.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: