Lemierre's Syndrome Associated with Periodontal Injury-derived Odontogenic Infection that Did Not Respond to Meropenem.

Abstract

A 33-year-old previously healthy man injured his gums and subsequently developed dyspnea and fever. A chest X-ray showed nodules and infiltrates in both lungs, and the patient was initially diagnosed with pneumonia and administered meropenem hydrate, although his symptoms did not improve. A blood culture identified Fusobacterium necrophorum, and thrombophlebitis in the internal jugular vein of the neck was observed on computed tomography and ultrasound scans. We replaced the meropenem with clindamycin, sulbactam/ampicillin and metronidazole, and the patient's symptoms improved.

• Authors: Morihiko Oya, Takao Tanimoto, Takayuki Yamamoto, Yukiya Hakozaki
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 54 Issue 14 Pg. 1803-8 ( 2015) ISSN: 1349-7235 [Electronic] Japan
• PMID: 26179541 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Thienamycins
• Metronidazole
• Clindamycin
• Meropenem

Topics

• Adult
• Anti-Bacterial Agents (administration & dosage)
• Clindamycin (administration & dosage)
• Dyspnea (etiology)
• Fever (etiology)
• Fusobacterium Infections (complications, drug therapy)
• Fusobacterium necrophorum (isolation & purification)
• Humans
• Jugular Veins (pathology)
• Lemierre Syndrome (diagnosis, etiology, microbiology)
• Male
• Meropenem
• Metronidazole (administration & dosage)
• Periodontitis (complications, microbiology)
• Radiography, Thoracic
• Thienamycins (administration & dosage)
• Tomography, X-Ray Computed
• Treatment Outcome
• Wound Infection (complications, microbiology)