[Properties of monoamine oxidase in the brain of mongolian gerbils during cerebral ischemia].

Properties of monoamine oxidase (MAO) were investigated in mongolian gerbils brain mitochondria isolated from cerebral cortex, striatum and hippocampus during cerebral ischemia. 5 min of ischemia caused inhibition of MAO activity (kynuramine as a substrate), alterations in substrate specificity and in kinetic curves form deflexion from hyperbolic type in all the brain structures investigated. Alterations in properties of MAO were observed in hippocampus already after I min of ischemia.
AuthorsI A Goroshinskaia, T Stoianovich, D V Michich, B B Mrshulia
JournalVoprosy medit︠s︡inskoĭ khimii (Vopr Med Khim) 1989 Sep-Oct Vol. 35 Issue 5 Pg. 112-5 ISSN: 0042-8809 [Print] USSR
Vernacular TitleSvoĭstva monoaminoksidazy v mozge mongol'skikh peschanok pri tserebral'noĭ ishemii.
PMID2617926 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Monoamine Oxidase Inhibitors
  • Monoamine Oxidase
  • Animals
  • Brain (enzymology)
  • Brain Ischemia (enzymology)
  • Deamination
  • Gerbillinae
  • Kinetics
  • Monoamine Oxidase (metabolism)
  • Monoamine Oxidase Inhibitors (metabolism)
  • Substrate Specificity

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