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Efficacy of RM110, a novel trypanocide, in the treatment of Trypanosoma evansi infections in camels.

Abstract
Camels artificially infected with a field stock of Trypanosoma evansi isolated from a camel near Gewane, Ethiopia were cured by treatment with RM110, administered by subcutaneous injection at 0.3 or 0.6 mg/kg body weight. Local reactions were mild and transient. Further evaluation of RM110 is indicated, in particular the determination of minimum curative doses for this and other T. evansi stocks in camels.
AuthorsD Zelleke, B Kassa, S Abebe
JournalTropical animal health and production (Trop Anim Health Prod) Vol. 21 Issue 4 Pg. 223-6 (Nov 1989) ISSN: 0049-4747 [Print] United States
PMID2617676 (Publication Type: Journal Article)
Chemical References
  • Arsenicals
  • Trypanocidal Agents
  • melaminylthioarsenate
Topics
  • Animals
  • Arsenicals (adverse effects, therapeutic use)
  • Body Weight (drug effects)
  • Camelus (parasitology)
  • Female
  • Hematocrit (veterinary)
  • Male
  • Mice
  • Trypanocidal Agents (adverse effects, therapeutic use)
  • Trypanosomiasis, African (blood, drug therapy, veterinary)

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