Successful Treatment of Dental Infection-Induced Chronic Cavernous Sinus Thrombophlebitis With Antibiotics and Low-Molecular-Weight Heparin: Two Case Reports.

Abstract

Two patients developed cavernous sinus thrombophlebitis from a tooth infection. A 36-year-old man experienced a severe headache with bilateral third and sixth cranial nerve palsies after extraction of his left upper third molar. Another 53-year-old diabetic man developed fever, headache, and bilateral complete ophthalmoplegia after a tooth infection. The brain magnetic resonance imaging scans of both patients showed bilateral cavernous sinus partial thrombosis. Broad-spectrum antibiotics plus low-molecular-weight heparin successfully resolved all symptoms. Both patients recovered fully without any recurrence at the 3-month follow-up visit.

• Authors: Yuan Li, Bo Zheng, Kangning Chen, Li Gui
• Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (J Oral Maxillofac Surg) Vol. 73 Issue 8 Pg. 1516-23 (Aug 2015) ISSN: 1531-5053 [Electronic] United States
• PMID: 26173405 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Chemical References

• Anti-Bacterial Agents
• Contrast Media
• Heparin, Low-Molecular-Weight

Topics

• Adult
• Anti-Bacterial Agents (therapeutic use)
• Bacterial Infections (complications, drug therapy)
• Cavernous Sinus Thrombosis (drug therapy, etiology)
• Contrast Media
• Heparin, Low-Molecular-Weight (therapeutic use)
• Humans
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Tooth Diseases (complications, drug therapy)
• Treatment Outcome