Advantages of treatment with Reprimun in sarcoidosis.

Abstract

Favourable results were obtained by treatment with Reprimun alone or in association with low doses of Prednisone in 112 patients with sarcoidosis (59% with active sarcoidosis and 33% failures of a previous corticotherapy). Treatments were applied during 3-6 series each one of 6 weeks at intervals of 2 weeks between series. In comparison with the classical corticotherapy, treatment with Reprimun has better results, namely: absence of any major adverse reactions; reduction of the treatment period to 6-12 months (3-6 series); 95% lasting remissions in the sarcoidoses with initial treatment and 78% remissions in the case of failures of a previous corticotherapy.

• Authors: E Păunescu, C Didilescu, F Mihălţan, S Udrea, A Serbescu, M Dănălache-Dumitrescu, M Smărăndache, M Stoinescu, C Zaharescu, A Petre
• Journal: Medecine interne (Med Interne) 1989 Jul-Sep Vol. 27 Issue 3 Pg. 225-8 ISSN: 0377-1202 [Print] Romania
• PMID: 2617077 (Publication Type: Journal Article)

Chemical References

• Rifamycins
• Reprimun
• Prednisone

Topics

• Adolescent
• Adult
• Child
• Drug Evaluation
• Drug Therapy, Combination
• Female
• Humans
• Lung Diseases (drug therapy)
• Male
• Mediastinal Diseases (drug therapy)
• Middle Aged
• Prednisone (therapeutic use)
• Remission Induction
• Rifamycins (therapeutic use)
• Sarcoidosis (drug therapy)