99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography.

Abstract

Total knee arthroplasty has witnessed a significant increase in recent years. Despite the advantages of this surgical procedure, it has some complications, the most serious of which is prosthetic infection. The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of periprosthetic infection (PPI). Ubiquicidin (UBI) is a synthetic antimicrobial peptide fragment reported to be highly infection-specific. Tc99m-UBI has recently been reported to be a promising radiotracer for infection imaging. We report a case of left knee PPI diagnosed using 99mTc-UBI scintigraphy and compared with F-18 fluorodeoxy-glucose positron emission tomography.

• Authors: Koramadai Karuppusamy Kamaleshwaran, N Rajkumar, Vyshak Mohanan, Radhakrishnan Kalarikal, Ajit Sugunan Shinto
• Journal: Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India (Indian J Nucl Med) 2015 Jul-Sep Vol. 30 Issue 3 Pg. 259-62 ISSN: 0972-3919 [Print] India
• PMID: 26170572 (Publication Type: Case Reports)