[Occupational cholangiocarcinoma in a printer that responded to neoadjuvant chemoradiotherapy].

Abstract

A 42-year-old man working at a printing company was referred to our hospital for examination and treatment of icterus. We diagnosed resectable hilar cholangiocarcinoma and provided neoadjuvant chemoradiotherapy, extended right hepatectomy, and extrahepatic bile duct resection. A detailed history revealed that he had used 1,2-dichloropropane as part of his work as an offset colour proof-printer, and he has subsequently been recognized as having occupational cholangiocarcinoma. He has survived without recurrence for more than 2 and half years since the liver resection. In the present report, we describe our valuable experience of neoadjuvant chemoradiotherapy for occupational cholangiocarcinoma.

• Authors: Kei Nakagawa, Yu Katayose, Kazuyuki Ishida, Hiroki Hayashi, Takanori Morikawa, Hiroshi Yoshida, Fuyuhiko Motoi, Takeshi Naitoh, Shoji Kubo, Michiaki Unno
• Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology (Nihon Shokakibyo Gakkai Zasshi) Vol. 112 Issue 7 Pg. 1341-7 (Jul 2015) ISSN: 0446-6586 [Print] Japan
• PMID: 26155867 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• propylene dichloride
• Propane

Topics

• Adult
• Bile Duct Neoplasms (chemically induced, therapy)
• Chemoradiotherapy, Adjuvant
• Cholangiocarcinoma (chemically induced, therapy)
• Humans
• Male
• Neoadjuvant Therapy
• Occupational Diseases (chemically induced, therapy)
• Printing
• Propane (analogs & derivatives, poisoning)