Abstract | BACKGROUND: METHODS: In this randomized, triple blind clinical trial of 70 non-pregnant women infected with Candidal vulvovaginitis were placed in two groups of Vaginal cream mixed of yogurt and honey recipients (N=35) and clotrimazole vaginal cream (N=35). Both groups were treated for 7 days. At the beginning of study, Clinical and laboratory signs and symptoms were registered 7 and 14 days after treatment by questionnaire, observation form and secretions culture results. Data by chi-square test, t test, McNemar tests were analyzed by SPSS version 21. Significance level of 0.05 was considered. RESULTS: The result of present study reveals the significant differences in symptom improvement of ' yogurt and honey, than clotrimazole group (P<0.05) and also Positive results of the first cultures (one week after treatment) in "yogurt and honey" and clotrimazole (20% versus 8.6%) and second time cultivation (14 days after treatment) (17/1% versus 8.6%) were similar and there was no significant differences between the two groups. (P>0.05) CONCLUSION: This study indicated that he therapeutic effects of vaginal cream, yogurt and honey is not only similar with clotrimazole vaginal cream but more effective in relieving some symptoms of vaginal candidiasis. Therefore, the use of this product can be suggested as an herbal remedy for candida infection treatment.
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Authors | Maryam Darvishi, Fereshteh Jahdi, Zeinab Hamzegardeshi, Saied Goodarzi, Mohsen Vahedi |
Journal | Global journal of health science
(Glob J Health Sci)
Vol. 7
Issue 6
Pg. 108-16
(Apr 03 2015)
ISSN: 1916-9736 [Print] Canada |
PMID | 26153168
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Antifungal Agents
- Vaginal Creams, Foams, and Jellies
- Clotrimazole
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Topics |
- Adult
- Antifungal Agents
(therapeutic use)
- Candidiasis, Vulvovaginal
(drug therapy)
- Clotrimazole
(therapeutic use)
- Female
- Honey
- Humans
- Treatment Outcome
- Vaginal Creams, Foams, and Jellies
(therapeutic use)
- Yogurt
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