Abstract | AIM OF THE STUDY: MATERIALS AND METHODS: Five patients with OL were included in the study. They were treated with 10% ALA mediated PDT (light source: Xenon lamp, power: 0.1 W, wavelength: 630 ± 5 nm, total dose: 100 J/cm(2) per session) for 6-8 sessions. Follow-up was done for a period of 1 year. RESULTS: One month (4 weeks) after ALA- PDT, the response was evaluated based on clinical examination. It was as follows: Complete response: Two patients; partial response: Two patients; and no response: One patient. There was no recurrence in any of the cases. CONCLUSION: There was satisfactory reduction in the size of the OL lesion without any side-effects. Thus, ALA mediated PDT seems to be a promising alternative for the treatment of OL.
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Authors | Niranzena Panneer Selvam, Jayachandran Sadaksharam, Ganesan Singaravelu, Rajasekaran Ramu |
Journal | Journal of cancer research and therapeutics
(J Cancer Res Ther)
2015 Apr-Jun
Vol. 11
Issue 2
Pg. 464-7
ISSN: 1998-4138 [Electronic] India |
PMID | 26148619
(Publication Type: Journal Article)
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Chemical References |
- Photosensitizing Agents
- Aminolevulinic Acid
|
Topics |
- Adult
- Aminolevulinic Acid
(therapeutic use)
- Carcinoma
(pathology, prevention & control)
- Humans
- Leukoplakia, Oral
(drug therapy, pathology)
- Male
- Middle Aged
- Mouth Neoplasms
(pathology, prevention & control)
- Photochemotherapy
(methods)
- Photosensitizing Agents
(therapeutic use)
- Pilot Projects
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