Topical Steroids Are Effective in the Treatment of Idiopathic Granulomatous Mastitis.

Abstract

BACKGROUND:

Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic disease of the breast. Despite the various treatment approaches described for this disease, a gold standard treatment modality has not yet been defined. In this study, the effect of topical steroids was reviewed and assessed in patients with IGM.

METHODS:

The records of patients with IGM who were treated only with topical steroids were retrospectively reviewed. Patients were grouped as "completely healed," "inadequately healed," "stable," "worsened," or "recurred" if they had once healed but their symptoms returned. Patients whose skin changes were completely ameliorated were considered "completely healed."

RESULTS:

All of the patients were women, and the average patient age was 35.7 years (range 24-48 years). During the average follow-up of 37.2 months (range 12-72 months) in patients who received only topical steroid treatment, recurrence was observed in three patients (3/28, 10.7 %), and no side effects or steroid-related complications occurred.

CONCLUSIONS:

Topical steroids seem to be effective in the treatment of IGM characterized by skin changes. Prospective clinical studies would be useful in determining the clinical efficacy of topical steroids in the treatment of IGM.

• Authors: Fatih Altintoprak, Taner Kivilcim, Omer Yalkin, Yener Uzunoglu, Zeynep Kahyaoglu, Osman Nuri Dilek
• Journal: World journal of surgery (World J Surg) Vol. 39 Issue 11 Pg. 2718-23 (Nov 2015) ISSN: 1432-2323 [Electronic] United States
• PMID: 26148520 (Publication Type: Journal Article)

Chemical References

• Steroids

Topics

• Administration, Cutaneous
• Adult
• Female
• Granulomatous Mastitis (drug therapy)
• Humans
• Middle Aged
• Recurrence
• Retrospective Studies
• Steroids (administration & dosage)
• Treatment Outcome
• Young Adult