Abstract | INTRODUCTION: CASE REPORT: A 64-year-old man with the 3-year history of bilateral Graves' orbitopathy and hyperthyroidism underwent the left orbital decompression surgery due to the predominantly left, unilateral worsening of exophthalmos resistant to the previously applied glucocorticoid therapy. A year after the surgical treatment, a substantial exophthalmos of the left eye was again observed, signifying that other non-thyroid pathology could be involved. Orbital ultrasound was suggestive of primary orbital lymphoma, what was confirmed by orbital CT scan and the biopsy of the tumor tissue. Detailed examinations indicated that the marginal zone B-cell non-Hodgkin lymphoma extended to IV - B-b CS, IPI 3 (bone marrow infiltration: m+ orbit+). Upon the completion of the polychemiotherapy and the radiation treatment, a complete remission of the disease was achieved. CONCLUSION: Even when elements clearly indicate the presence of thyroid-related ophthalmopathy, disease deteriorating should raise a suspicion and always lead to imaging procedures to exclude malignancy.
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Authors | Zoran Hajduković, Snežana Kuzmić-Janković, Tamara Kljaković-Avramović, Leposava Sekulović, Ljiljana Tukić |
Journal | Vojnosanitetski pregled
(Vojnosanit Pregl)
Vol. 71
Issue 5
Pg. 510-4
(May 2014)
ISSN: 0042-8450 [Print] Serbia |
PMID | 26137719
(Publication Type: Case Reports, Journal Article)
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Topics |
- Diagnosis, Differential
- Diagnostic Imaging
- Graves Ophthalmopathy
(diagnosis, pathology, therapy)
- Humans
- Lymphoma
(diagnosis, pathology, therapy)
- Lymphoma, B-Cell, Marginal Zone
(diagnosis, pathology, therapy)
- Male
- Middle Aged
- Orbital Neoplasms
(diagnosis, pathology, therapy)
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