Pyoderma gangrenosum in an allogeneic bone marrow transplant recipient.

We present the case of a 15-year-old boy who developed facial pyoderma gangrenosum following an allogeneic bone marrow transplantation for the treatment of a 'blast' crisis developing in the course of chronic myelogenous leukaemia. The lesion appeared 7 months before any evidence of relapse. The discussion is focused on both the presentation of pyoderma gangrenosum associated with myelo-proliferative disorders and its pathogenesis via the underlying immunosuppression.
AuthorsD Blanc, M Schreiber, E Racadot, J Y Kahn, M Flesch, G Viennet, M Lab, M Zultak
JournalClinical and experimental dermatology (Clin Exp Dermatol) Vol. 14 Issue 5 Pg. 376-9 (Sep 1989) ISSN: 0307-6938 [Print] ENGLAND
PMID2612043 (Publication Type: Case Reports, Journal Article)
  • Adolescent
  • Bone Marrow Transplantation (adverse effects)
  • Facial Dermatoses (pathology)
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive (surgery)
  • Male
  • Necrosis
  • Pyoderma (pathology)
  • T-Lymphocytes (pathology)

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