Abstract | BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is rapidly gaining popularity. Estimating the risk of postoperative adverse events can improve surgical decision-making and informed patient consent. The objective of this study was to develop and validate a risk prediction model for early postoperative morbidity and mortality after LSG. METHODS: Cases of primary LSG in the American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) data set at year 2012 (n = 5871) and 2011 (n = 3130) were identified to develop and examine the validity of model. The composite primary outcome was defined as presence of any of 14 serious adverse events within the 30-days after LSG. Multiple logistic regression analysis was performed and a risk calculator was created to predict the primary outcome. RESULTS: Thirty-day postoperative mortality and composite adverse events rates of 5871 LSG cases were .05% and 2.4%, respectively. Of the 52 examined baseline variables, the final model contained history of congestive heart failure (odds ratio [OR] 6.23; 95% CI 1.25-31.07), chronic steroid use (OR 5.00; 95% CI 2.06-12.15), male sex (OR 1.68; 95% CI 1.03-2.72), diabetes (OR 1.62; 95% CI 1.07-2.48), preoperative serum total bilirubin level (OR 1.57; 95% CI 1.11-2.22), body mass index (OR 1.03; 95% CI 1.01-1.05), and preoperative hematocrit level (OR .95; 95% CI .89-1.00). The risk model was then validated with the 2011 data set and was used to create an online risk calculator with a relatively good accuracy (c-statistic .682). CONCLUSIONS: This risk assessment scoring system, which specifically estimates serious adverse events after LSG, can contribute to surgical decision-making, informed patient consent, and prediction of surgical risk for patients and referring physicians.
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Authors | Ali Aminian, Stacy A Brethauer, Maryam Sharafkhah, Philip R Schauer |
Journal | Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
(Surg Obes Relat Dis)
2015 Jul-Aug
Vol. 11
Issue 4
Pg. 758-64
ISSN: 1878-7533 [Electronic] United States |
PMID | 26117166
(Publication Type: Journal Article, Multicenter Study)
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Copyright | Copyright © 2015. Published by Elsevier Inc. |
Topics |
- Adult
- Female
- Gastrectomy
(methods)
- Humans
- Laparoscopy
(methods)
- Male
- Morbidity
(trends)
- Obesity, Morbid
(surgery)
- Odds Ratio
- Outcome Assessment, Health Care
- Postoperative Complications
(epidemiology)
- Reproducibility of Results
- Retrospective Studies
- Risk Assessment
(methods)
- Risk Factors
- Survival Rate
(trends)
- Treatment Outcome
- United States
(epidemiology)
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