High-Flow Nasal Cannula and Aerosolized β Agonists for Rescue Therapy in Children With Bronchiolitis: A Case Series.

Abstract

Asthma and bronchiolitis are episodic obstructive pulmonary diseases characterized by bronchoconstriction, airway wall inflammation, increased mucus production, and air-flow obstruction. We present the cases of 5 infants treated for acute bronchiolitis with respiratory distress using a combination of high-flow nasal cannula oxygen (HFNC) and an Aerogen nebulizer to deliver aerosolized β-agonist therapy. In all infants, we found that HFNC resulted in a greater heart rate increase than delivery via a facemask. We also found that patients tolerated inhaled therapy better with HFNC than a facemask.

• Authors: Sherwin E Morgan, Steve Mosakowski, Patti Solano, Jesse B Hall, Avery Tung
• Journal: Respiratory care (Respir Care) Vol. 60 Issue 9 Pg. e161-5 (Sep 2015) ISSN: 1943-3654 [Electronic] United States
• PMID: 26106204 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 by Daedalus Enterprises.

Chemical References

• Adrenergic beta-2 Receptor Agonists
• Nasal Sprays

Topics

• Adrenergic beta-2 Receptor Agonists (administration & dosage)
• Bronchiolitis (therapy)
• Catheters
• Female
• Humans
• Infant
• Male
• Nasal Sprays
• Nebulizers and Vaporizers
• Oxygen Inhalation Therapy (instrumentation)
• Respiratory Distress Syndrome, Newborn (therapy)
• Salvage Therapy (methods)