Abstract |
Several antimicrobial agents are being investigated as alternatives to carbapenems in the treatment of infections caused by ESBL-producing Enterobacteriaceae, which may be useful in avoiding overuse of carbapenems in the context of recent global spread of carbapenem-resistant Enterobacteriaceae. The most promising candidates for invasive infections so far are β- lactam/β-lactamase inhibitor combinations and cephamycins.
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Authors | Jesús Rodríguez-Baño |
Journal | Antimicrobial agents and chemotherapy
(Antimicrob Agents Chemother)
Vol. 59
Issue 9
Pg. 5095-6
(Sep 2015)
ISSN: 1098-6596 [Electronic] United States |
PMID | 26100709
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2015, American Society for Microbiology. All Rights Reserved. |
Chemical References |
- Anti-Bacterial Agents
- Carbapenems
- Cephamycins
- beta-Lactamase Inhibitors
- beta-Lactamases
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Topics |
- Anti-Bacterial Agents
(pharmacology)
- Carbapenems
(pharmacology)
- Cephamycins
(pharmacology)
- Enterobacteriaceae
(drug effects, enzymology)
- Microbial Sensitivity Tests
- beta-Lactamase Inhibitors
(pharmacology)
- beta-Lactamases
(metabolism)
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