[The effect of batriden and dexasone on immune status indices in animals with experimental allergic contact dermatitis].

Abstract

Experimental findings evidence that the immunity parameters of guinea pigs with 2,4-DNCB-induced allergic contact dermatitis normalize after batriden and dexason therapy, immunosuppressant batriden in low doses alleviating the marked lymphopenic effect of dexason and its inhibitory effect on the peripheral blood neutrophil phagocytic activity. Use of this drug complex will help reduce the hormone dose and thus eliminate the undesirable effects of hormone therapy of allergic diseases of the skin.

• Authors: S A Allamiiarova, K G Urazmetov
• Journal: Vestnik dermatologii i venerologii (Vestn Dermatol Venerol) Issue 10 Pg. 8-10 ( 1989) ISSN: 0042-4609 [Print] Russia (Federation)
• Vernacular Title: Vliianie batridena i deksazonom na nekotorye pokazateli immunnogo statusa zhivotnykh s éksperimental'nym allergicheskim kontaktnym dermatitom.
• PMID: 2609756 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Immunosuppressive Agents
• batridene
• Dexamethasone
• Gossypol

Topics

• Animals
• B-Lymphocytes (drug effects, immunology)
• Dermatitis, Contact (drug therapy, immunology)
• Dexamethasone (therapeutic use)
• Drug Evaluation, Preclinical
• Gossypol (analogs & derivatives)
• Guinea Pigs
• Immunity, Cellular (drug effects, immunology)
• Immunosuppressive Agents (therapeutic use)
• T-Lymphocytes (drug effects, immunology)