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HLA Bw57 and DR7 association with psoriasis vulgaris in south India.

Abstract
Eighty-three south Indian patients with psoriasis vulgaris were studied for HLA antigen frequencies and compared with 77 controls studied simultaneously. HLA Bw57, a split of B17 was found elevated in the patients. The two sexes differed in their age-at-onset curves: females had a preponderance to early onset of the disease, while the males had late onset. Among these patients, major group 3, a Western Brachycephal Armenoid group, revealed the highest risk for B17 & Bw57 but not major group 2, a Mediterranean one.
AuthorsR M Pitchappan, A Koteeswaran, V N Kakkaniah, M Manickasundari, V Rajaram, P Muthuveeralakshmi, V Mahendran, V Brahmajothibai
JournalTissue antigens (Tissue Antigens) Vol. 34 Issue 2 Pg. 133-7 (Aug 1989) ISSN: 0001-2815 [Print] England
PMID2609323 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • HLA-B Antigens
  • HLA-B57 antigen
  • HLA-DR7 Antigen
Topics
  • Adult
  • Female
  • HLA-B Antigens (analysis)
  • HLA-DR7 Antigen (analysis)
  • Humans
  • India
  • Male
  • Phenotype
  • Psoriasis (immunology)

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