[Clinical effects of cefodizime against infectious diseases in obstetrics and gynecology].

Abstract

Clinical studies on cefodizime (CDZM) were performed in patients of obstetrics and gynecology. CDZM was given to patients via drip infusion at a daily dose of 2-4 g, and the results obtained are summarized as follows: 1. A total of 10 cases included 5 cases of intrauterine infections (3 cases of puerperal endometritis, 1 endometritis and 1 puerperal fever), 2 intrapelvic infections (1 pelvic dead space infection and 1 parametritis), and 3 Bartholin's abscess. Clinical efficacies were excellent in 3 cases, good in 6 and poor in 1. The efficacy rate was 90% (9/10). 2. Bacteriological efficacies were as follows: eradicated in 3 cases, replaced in 2, decreased in 1, persisted in 1 and unknown in 3. 3. Neither subjective and objective adverse reactions nor abnormal changes in laboratory test values were observed.

• Authors: T Chimura, N Morisaki, T Hirayama, M Matsuo
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 42 Issue 10 Pg. 2065-8 (Oct 1989) ISSN: 0368-2781 [Print] Japan
• PMID: 2607596 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Clindamycin
• Aztreonam
• Cefotaxime
• cefodizime

Topics

• Adolescent
• Adult
• Aged
• Aztreonam (administration & dosage)
• Bacteria (isolation & purification)
• Bacterial Infections (drug therapy, microbiology)
• Cefotaxime (administration & dosage, analogs & derivatives, therapeutic use)
• Clindamycin (administration & dosage)
• Drug Evaluation
• Female
• Genital Diseases, Female (drug therapy, microbiology)
• Humans
• Infusions, Intravenous
• Middle Aged