The purpose of this study is to assess the technical feasibility and clinical efficacy of percutaneous transluminal angioplasty and stenting (PTAS) for symptomatic
stenosis of the intracranial extradural (petrous and cavernous) internal carotid artery (ICA).Review of medical records identified 26 consecutive patients who underwent PTAS using a balloon-expandable coronary
stent (n = 15, 57.7%) or a Wingspan self-expandable
stent (n = 11, 42.3%) for treatment of severe
stenosis (>70%) involving the intracranial extradural ICA. The inclusion criteria were
transient ischemic attack with an ABCD(2) score of ≥3 (n = 12, 46.2%) or minor
stroke with an NIHSS score of ≤4 (n = 14, 53.8%). Technical success rates, complications, and angiographic and clinical outcomes were analyzed retrospectively.PTAS was technically successful in all patients. The mean
stenosis ratio decreased from 77.1% to 10.0% immediately after PTAS. The overall incidence of procedural complications was 23.1%, and the postoperative permanent morbidity/mortality rate was 7.7%. A total of 22 patients were tracked over an average period of 29.9 months. During the observation period, 20 patients (90.9%) had no further cerebrovascular events and
stroke recurrence occurred in two patients (9.1%), resulting in an annual
stroke risk of 3.7%. Two cases (11.1%) of significant in-
stent restenosis (>50%) were found on follow-up angiography (n = 18).PTAS for severe
stenosis (>70%) involving the intracranial extradural ICA showed a good technical feasibility and favorable clinical outcome in patients with
transient ischemic attack or minor
stroke.