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[Effects of different-frequency-electroacupuncture and moxibustion stimulation of "Neiguan" (PC 6) on arrhythmia in rabbits].

AbstractOBJECTIVE:
To observe the effect of different-frequency-electroacupuncture (EA) and moxibustion stimulation on rabbits' arrhythmias.
METHODS:
Newzealand rabbits were randomly divided into arrhythmia model (n = 18), EA-3 Hz (n = 19), EA-20 Hz (n = 19), EA-100 Hz (n = 18) and moxibustion (n = 18) groups. The arrhythmia model was induced by intravenous injection of 25 μg/kg aconitine. EA (3 Hz, 20 Hz or 100 Hz, 3.5-4 V) or moxibustion was applied to bilateral "Neiguan" (PC 6) for 20 min and electrocardiogram (ECG) of the standard limb lead II was recorded by using a Biosignal Processing Instrument. The concentration of serum hypersensitive C reactive protein (hs-CRP) content was detected by using ELISA method.
RESULTS:
Following EA intervention, the duration of aconitine-induced arrhythmia was significantly shorter in both EA-20 Hz and EA-100 Hz groups than in the model group (P < 0.05, P < 0.01), and the serum hs-CRP level in the EA-20 Hz group was significantly lower than that of the model group ( P < 0.05). No significant changes were found in the duration of arrhythmia in both EA-3 Hz and moxibustion groups, and in the serum hs-CRP level in the EA-3 Hz, EA-100.Hz and the moxibustion groups (P > 0. 05).
CONCLUSION:
EA stimulation of PC 6 at 20 Hz and 100 Hz has an anti-arrhythmic effect in aconitine-induced arrhythmia rabbits.
AuthorsLing Chen, Jin-Sen Xu, Cai-Lian Lan, Xiao-Hua Pan
JournalZhen ci yan jiu = Acupuncture research (Zhen Ci Yan Jiu) Vol. 40 Issue 2 Pg. 146-50 (Apr 2015) ISSN: 1000-0607 [Print] China
PMID26054201 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • C-Reactive Protein
Topics
  • Acupuncture Points
  • Animals
  • Arrhythmias, Cardiac (metabolism, physiopathology, therapy)
  • C-Reactive Protein (metabolism)
  • Combined Modality Therapy
  • Electroacupuncture (instrumentation, methods)
  • Electrocardiography
  • Humans
  • Male
  • Moxibustion
  • Rabbits

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