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Identification of meso-hydroxyuroporphyrin I in the urine of a patient with congenital erythropoietic porphyria.

Abstract
A new porphyrin, meso-hydroxyuroporphyrin I, was isolated from the urine of a patient with congenital erythropoietic porphyria. The structure was characterized as the methyl ester, ethyl ester and acetoxy derivatives by fast-atom-bombardment m.s., by conversion into uroporphyrin I and by chemical synthesis.
AuthorsR Guo, J M Rideout, C K Lim
JournalThe Biochemical journal (Biochem J) Vol. 264 Issue 1 Pg. 293-5 (Nov 15 1989) ISSN: 0264-6021 [Print] England
PMID2604713 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Porphyrins
  • Uroporphyrins
  • hydroxyuroporphyrin I
Topics
  • Adolescent
  • Chemical Phenomena
  • Chemistry
  • Chromatography, High Pressure Liquid
  • Humans
  • Male
  • Mass Spectrometry
  • Porphyrias (genetics, urine)
  • Porphyrins (urine)
  • Uroporphyrins (urine)

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