Epstein-Barr Virus-Associated Pulmonary Smooth Muscle Tumor After Lung Transplantation.

Abstract

We report an Epstein-Barr virus (EBV)-associated pulmonary posttransplant smooth muscle tumor arising in the left lung of a 71-year-old bilateral lung transplant recipient nearly 3 years after transplantation, treated with thoracoscopic wedge resection. Four previous smooth muscle tumors have been reported following lung transplantation. To our knowledge, this is the first reported case of an EBV-positive posttransplant smooth muscle tumor within the transplanted lung. We describe the clinical, pathologic, and histologic diagnosis of this uncommon tumor.

• Authors: Alexander A Brescia, Onkar V Khullar, Anthony A Gal, David Neujahr, Seth D Force
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 99 Issue 6 Pg. e145-6 (Jun 2015) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 26046906 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Chemical References

• Antibodies, Viral

Topics

• Aged
• Antibodies, Viral (analysis)
• Diagnosis, Differential
• Epstein-Barr Virus Infections (diagnosis, surgery, virology)
• Herpesvirus 4, Human (immunology)
• Humans
• Lung Neoplasms (diagnosis, surgery, virology)
• Lung Transplantation (adverse effects)
• Male
• Pneumonectomy
• Positron-Emission Tomography
• Smooth Muscle Tumor (diagnosis, surgery, virology)
• Tomography, X-Ray Computed