Plasma 19-hydroxyandrostenedione and androstenedione levels in hydatidiform moles and early pregnancies with and without hypertensive diseases.

Abstract

Because of the association of preeclampsia with hydatidiform mole, and since levels of 19-hydroxyandrostenedione (19-OH-A) and androstenedione (A) are raised in hypertensive diseases of pregnancy, we compared plasma 19-OH-A and A in hydatidiform mole patients with control early pregnant women. Both steroids were significantly elevated in 27 patients with partial or complete hydatidiform moles, as compared with the levels in 36 control pregnancies at similar stages of gestation.

• Authors: M E Hähnel, J D Martin, R Hähnel
• Journal: The Australian & New Zealand journal of obstetrics & gynaecology (Aust N Z J Obstet Gynaecol) Vol. 29 Issue 3 Pt 1 Pg. 238-41 (Aug 1989) ISSN: 0004-8666 [Print] Australia
• PMID: 2604654 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Androstenedione
• 19-hydroxy-4-androstene-3,17-dione

Topics

• Androstenedione (analogs & derivatives, blood)
• Female
• Humans
• Hydatidiform Mole (blood, complications)
• Hypertension (blood)
• Pregnancy
• Pregnancy Complications, Cardiovascular (blood)
• Uterine Neoplasms (blood, complications)