Abstract | PURPOSE: The aim of this present study was to evaluate the sonographic correlation between Doppler flow characteristics of the uterine arteries and tumor size in patients with cervical cancer, in order to establish a new potential marker to monitor treatment response. METHODS: This was a retrospective cohort study of 25 patients who underwent a sonographic evaluation of Doppler flow characteristics of the uterine arteries before surgery or radiochemotherapy for early and locally advanced/advanced cervical cancer, respectively, was analyzed. The primary outcome was the correlation between Doppler flow characteristics of the uterine arteries and tumor size in patients with cervical cancer. RESULTS: Median age was 49 (range 26-85) years, and mean tumor size was 40.8 ± 17 mm. A significant positive correlation was found between tumor diameter and the uterine artery end-diastolic velocity (r = 0.47, p < 0.05) as well as the peak systolic velocity (r = 0.41, p < 0.05). No correlation was found between tumor size and the pulsatility index or resistance index. CONCLUSIONS:
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Authors | Daniele Bolla, Sarah In-Albon, Andrea Papadia, Edoardo Di Naro, Maria Luisa Gasparri, Michael M Mueller, Luigi Raio |
Journal | Annals of surgical oncology
(Ann Surg Oncol)
Vol. 22 Suppl 3
Pg. S959-63
(Dec 2015)
ISSN: 1534-4681 [Electronic] United States |
PMID | 26036189
(Publication Type: Journal Article)
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Topics |
- Adenocarcinoma
(diagnostic imaging, pathology, therapy)
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Carcinoma, Squamous Cell
(diagnostic imaging, pathology, therapy)
- Chemoradiotherapy
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Neoplasm Grading
- Neoplasm Staging
- Prognosis
- Retrospective Studies
- Tumor Burden
- Ultrasonography, Doppler, Color
(methods)
- Uterine Cervical Neoplasms
(diagnostic imaging, pathology, therapy)
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