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Tamoxifen-associated hirsutism: an unusual side effect in a 5-year-old girl with McCune-Albright syndrome.

Abstract
Tamoxifen, a selective estrogen receptor modulator, has been used in the treatment of peripheral precocious puberty. A 5-year and 3-month-old girl, diagnosed with McCune-Albright syndrome, came in with abnormal hair growth approximately 2 months after the initiation of tamoxifen. The pattern of terminal hair on the skin following the administration of the drug and the exclusion of other causes suggested tamoxifen-induced hirsutism.
AuthorsHeves Kırmızıbekmez, Rahime Gül Yesiltepe Mutlu, Fatma Dursun, Şükriye Pınar İşgüven
JournalJournal of pediatric endocrinology & metabolism : JPEM (J Pediatr Endocrinol Metab) Vol. 28 Issue 9-10 Pg. 1191-3 (Sep 2015) ISSN: 2191-0251 [Electronic] Germany
PMID26024247 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Selective Estrogen Receptor Modulators
  • Tamoxifen
Topics
  • Child, Preschool
  • Female
  • Fibrous Dysplasia, Polyostotic (drug therapy)
  • Hirsutism (chemically induced)
  • Humans
  • Selective Estrogen Receptor Modulators (adverse effects, therapeutic use)
  • Tamoxifen (adverse effects, therapeutic use)

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