Persistent Legionnaire's disease in an adult with hairy cell leukemia successfully treated with prolonged levofloxacin therapy.

Abstract

Legionnaire's disease (LD) manifests most commonly as an atypical community acquired pneumonia (CAP) with systemic extrapulmonary manifestations. Disorders associated with impaired cell mediated immunity (CMI) are particularly predisposed to LD. Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative leukemia associated with decreased CMI. LD has only rarely been reported in HCL. We present a most interesting case of persistent LD in a elderly male with HCL who required prolonged antibiotic therapy.

• Authors: Burke A Cunha, Sigridh Munoz-Gomez, Arthur Gran, Muhammad Raza, Nadia Irshad
• Journal: Heart & lung : the journal of critical care (Heart Lung) 2015 Jul-Aug Vol. 44 Issue 4 Pg. 360-2 ISSN: 1527-3288 [Electronic] United States
• PMID: 26021547 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 Elsevier Inc. All rights reserved.

Chemical References

• Anti-Bacterial Agents
• Levofloxacin

Topics

• Aged
• Anti-Bacterial Agents (therapeutic use)
• Chronic Disease
• Community-Acquired Infections (complications, drug therapy)
• Humans
• Legionnaires' Disease (complications)
• Leukemia, Hairy Cell (complications, drug therapy)
• Levofloxacin (therapeutic use)
• Male
• Pneumonia, Bacterial (complications, drug therapy)
• Treatment Outcome