Determination of benefits of cochlear implantation in children with auditory neuropathy.

Abstract

BACKGROUND:

Auditory neuropathy (AN) is a recently recognized hearing disorder characterized by intact outer hair cell function, disrupted auditory nerve synchronization and poor speech perception and recognition. Cochlear implants (CIs) are currently the most promising intervention for improving hearing and speech in individuals with AN. Although previous studies have shown optimistic results, there was large variability concerning benefits of CIs among individuals with AN. The data indicate that different criteria are needed to evaluate the benefit of CIs in these children compared to those with sensorineural hearing loss. We hypothesized that a hierarchic assessment would be more appropriate to evaluate the benefits of cochlear implantation in AN individuals.

METHODS:

Eight prelingual children with AN who received unilateral CIs were included in this study. Hearing sensitivity and speech recognition were evaluated pre- and postoperatively within each subject. The efficacy of cochlear implantation was assessed using a stepwise hierarchic evaluation for achieving: (1) effective audibility, (2) improved speech recognition, (3) effective speech, and (4) effective communication.

RESULTS:

The postoperative hearing and speech performance varied among the subjects. According to the hierarchic assessment, all eight subjects approached the primary level of effective audibility, with an average implanted hearing threshold of 43.8 ± 10.2 dB HL. Five subjects (62.5%) attained the level of improved speech recognition, one (12.5%) reached the level of effective speech, and none of the subjects (0.0%) achieved effective communication.

CONCLUSION:

CIs benefit prelingual children with AN to varying extents. A hierarchic evaluation provides a more suitable method to determine the benefits that AN individuals will likely receive from cochlear implantation.

• Authors: Fei Ji, Jianan Li, Mengdi Hong, Aiting Chen, Qingshan Jiao, Li Sun, Sichao Liang, Shiming Yang
• Journal: PloS one (PLoS One) Vol. 10 Issue 5 Pg. e0127566 ( 2015) ISSN: 1932-6203 [Electronic] United States
• PMID: 26010832 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Child, Preschool
• Cochlear Implants
• Female
• Hearing
• Hearing Loss, Central (physiopathology, therapy)
• Humans
• Infant
• Learning
• Male
• Speech Perception