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Smart Albumin-Biomineralized Nanocomposites for Multimodal Imaging and Photothermal Tumor Ablation.

Abstract
Smart cyanine-grafted gadolinium oxide nanocrystals (Cy-GdNCs) obtained by albumin-based biomineralization are shown to be theranostic nanocomposites, with promising properties for trimodal near-infrared fluorescence/photoacoustics/magnetic-resonance imaging-guided photothermal tumor ablation.
AuthorsYong Wang, Tao Yang, Hengte Ke, Aijun Zhu, Yangyun Wang, Junxin Wang, Junkang Shen, Gang Liu, Chunying Chen, Yuliang Zhao, Huabing Chen
JournalAdvanced materials (Deerfield Beach, Fla.) (Adv Mater) Vol. 27 Issue 26 Pg. 3874-82 (Jul 08 2015) ISSN: 1521-4095 [Electronic] Germany
PMID25997571 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Copyright© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Chemical References
  • Cypate
  • Indoles
  • Minerals
  • Propionates
  • Serum Albumin, Bovine
  • gadolinium oxide
  • Gadolinium
Topics
  • Ablation Techniques (methods)
  • Animals
  • Cattle
  • Cell Line, Tumor
  • Gadolinium (chemistry)
  • Hydrogen-Ion Concentration
  • Indoles (chemistry)
  • Mammary Neoplasms, Experimental (diagnosis, pathology, therapy)
  • Mice
  • Minerals (chemistry, metabolism)
  • Models, Molecular
  • Multimodal Imaging (methods)
  • Nanocomposites (chemistry, therapeutic use)
  • Nanoparticles (chemistry)
  • Phototherapy
  • Propionates (chemistry)
  • Protein Conformation
  • Serum Albumin, Bovine (chemistry, metabolism)
  • Theranostic Nanomedicine

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