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Successful renal transplantation in Muckle-Wells syndrome treated with anti-IL-1β-monoclonal antibody.

Abstract
We report the first case of a 32-year-old woman with Muckle-Wells syndrome and biopsy-proven systemic AA amyloidosis and end-stage renal disease. She was treated with canakinumab 150 mg subcutaneously every 8 weeks and underwent renal transplantation. Fourteen months after renal transplanation, the patient had no flares of Muckle-Wells syndrome and no evidence of amyloidosis in the renal transplant under an excellent graft function and therapy with canakinumab.
AuthorsBirgit Kortus-Götze, Joachim Hoyer
JournalNDT plus (NDT Plus) Vol. 4 Issue 6 Pg. 404-5 (Dec 2011) ISSN: 1753-0784 [Print] England
PMID25984207 (Publication Type: Case Reports)

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