[The possibility of using PlasmaDeepDive™ MRM panel in clinical diagnostics].

Abstract

Concentrations of 46 proteins have been determined in human blood plasma using PlasmaDeepDive™ MRM Panel ("Biognosys AG", Switzerland). 18 of them were included into the group of proteins with higher concentrations, also identified by the shotgun proteomic analysis. Based on literature data it is concluded that the PlasmaDeepDive™ MRM Panel is applicable for studies of human plasma samples for potential biomarkers of various nervous system disorders.

• Authors: Iu V Miroshnichenko, N A Petushkova, N E Moskaleva, N B Teryaeva, V G Zgoda, E V Ilgisonis, A Yu Belyaev
• Journal: Biomeditsinskaia khimiia (Biomed Khim) 2015 Mar-Apr Vol. 61 Issue 2 Pg. 272-8 ISSN: 2310-6972 [Print] Russia (Federation)
• PMID: 25978393 (Publication Type: English Abstract, Journal Article)

Chemical References

• Blood Proteins

Topics

• Blood Proteins (analysis)
• Humans
• Mass Spectrometry (instrumentation, methods)
• Proteomics (methods)
• Tandem Mass Spectrometry (methods)