Hypercalciuria in a child with acral peeling skin syndrome: a case report.

Abstract

We present a case of 3-year-old Caucasian boy who developed monthly cyclic attacks of skin peeling of the palms and soles over 1.5 years. The skin peeling was associated with hypercalciuria. No mutation was present in TGM5 and CSTA genes, but the typical clinical picture and the biopsy from flaccid blisters on the feet confirmed the acral peeling skin syndrome (APSS). The possible associations of rare genetic disorders and metabolic conditions in the course of APSS need to be investigated.

• Authors: Daiva Gorczyca, Jolanta Węgłowska, Anna Prescha, Zdzisław Woźniak, Dominika Nesteruk, Katarzyna Wertheim-Tysarowska, Robert Śmigiel
• Journal: Acta dermatovenerologica Croatica : ADC (Acta Dermatovenerol Croat) Vol. 23 Issue 1 Pg. 59-62 ( 2015) ISSN: 1847-6538 [Electronic] Croatia
• PMID: 25969915 (Publication Type: Case Reports, Journal Article)

Topics

• Child, Preschool
• Humans
• Hypercalciuria (complications, diagnosis, therapy)
• Male
• Skin Diseases (congenital, etiology, pathology, therapy)