Low-grade serous primary peritoneal carcinoma incidentally found in a hernia sac.

Abstract

Very rarely, a primary peritoneal serous carcinoma can be observed in a hernia sac. We herein describe a low-grade serous primary peritoneal carcinoma incidentally found in a postmenopausal woman following examination of the femoral hernia repair sac. Our case is significant for its unusual presentation. The lesion initially appeared as a 0.3-cm tumor that disseminated in the peritoneum, persisted, and progressed for 75 months. The absence of ovarian disease indicated a primary peritoneal origin. Tumor cells were immunohistochemically positive for PAX8, claudin-4, and VE1, excluding the possibility of being of mesothelial origin. Recognition that a low-grade serous primary peritoneal carcinoma can be incidentally found in a hernia sac should simplify future diagnoses. Immunohistochemistry is helpful in making the correct diagnosis.

• Authors: José-Fernando Val-Bernal, Marta Mayorga, Daniel Val, María-Francisca Garijo
• Journal: Pathology, research and practice (Pathol Res Pract) Vol. 211 Issue 7 Pg. 550-5 (Jul 2015) ISSN: 1618-0631 [Electronic] Germany
• PMID: 25953339 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 Elsevier GmbH. All rights reserved.

Chemical References

• Biomarkers, Tumor

Topics

• Biomarkers, Tumor (analysis)
• Cystadenocarcinoma, Serous (complications, pathology)
• Female
• Hernia, Femoral (complications)
• Humans
• Immunohistochemistry
• Incidental Findings
• Middle Aged
• Neoplasm Grading
• Neoplasm Recurrence, Local (pathology)
• Peritoneal Neoplasms (complications, pathology)