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Influence of selenium status in merino weaners on resistance to trichostrongylid infection.

Abstract
Weaned merino lambs, grazing pastures low in selenium, were used to investigate the effect of selenium status on immunity to trichostrongylids. Six weeks following selenium supplementation to 14 of the 27 sheep using intraruminal selenium pellets, 5000 Ostertagia circumcincta and 5000 Trichostrongylus colubriformis larvae were administered orally to all sheep. At four weeks after infection, the mean total worm burden in the selenium supplemented sheep (5537 +/- 343, n = 14) was not significantly different (P greater than 0.05) from that in the unsupplemented sheep (5614 +/- 374, n = 12) and faecal worm egg concentrations were also similar in the two treatment groups. At this time, mean red cell glutathione peroxidase activities in the supplemented and unsupplemented groups were 430 and 11 U g-1 haemoglobin, respectively, and clinical white muscle disease had been observed in the latter group. These results suggest that increasing selenium status of selenium deficient sheep by the use of intraruminal selenium supplementation, has a negligible effect on resistance to an artificial challenge infection of O circumcincta and T colubriformis.
AuthorsJ W McDonald, D J Overend, D I Paynter
JournalResearch in veterinary science (Res Vet Sci) Vol. 47 Issue 3 Pg. 319-22 (Nov 1989) ISSN: 0034-5288 [Print] England
PMID2595090 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Pepsinogens
  • Ovalbumin
  • Glutathione Peroxidase
  • Selenium
Topics
  • Animals
  • Body Weight
  • Erythrocytes (enzymology)
  • Feces (parasitology)
  • Glutathione Peroxidase (blood)
  • Ostertagiasis (immunology, veterinary)
  • Ovalbumin (immunology)
  • Parasite Egg Count (veterinary)
  • Pepsinogens (blood)
  • Selenium (administration & dosage, deficiency)
  • Sheep
  • Sheep Diseases (immunology)
  • Trichostrongyloidiasis (veterinary)
  • Trichostrongylosis (immunology, veterinary)
  • Weaning

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