Abstract | BACKGROUND: Parthenium hysterophorus is the leading cause of phytogenic allergic contact dermatitis in India. The Indian Standard Series currently supplied by Systopic Laboratories Ltd and manufactured by Chemotechnique Diagnostics ® contains parthenolide as the only allergen representing plant allergens. AIM: The study was conducted to assess the performance of the Chemotechnique plant series (PL-1000), consisting of 14 allergens, in patients with clinically suspected occupational contact dermatitis to plant allergens. METHODS: Ninety patients were patch tested with the Chemotechnique plant series from 2011 to 2013. Demographic details, clinical diagnosis and patch test results were recorded in the contact dermatitis clinic proforma. RESULTS: Of 90 patients, 24 (26.7%) showed positive reactions to one or more allergens in the plant series. Positive patch tests were elicited most commonly by sesquiterpene lactone mix in 19 (78.6%) patients, followed by parthenolide in 14 (57.1%), Achillea millefolium in 10 (42.9%) and others in decreasing order. CONCLUSION:
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Authors | Dipankar De, Geeti Khullar, Sanjeev Handa |
Journal | Indian journal of dermatology, venereology and leprology
(Indian J Dermatol Venereol Leprol)
2015 Jul-Aug
Vol. 81
Issue 4
Pg. 376-9
ISSN: 0973-3922 [Electronic] United States |
PMID | 25937142
(Publication Type: Evaluation Study, Journal Article)
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Chemical References |
- Allergens
- Lactones
- Sesquiterpenes
- parthenolide
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Topics |
- Achillea
(immunology)
- Adult
- Allergens
(adverse effects, immunology)
- Asteraceae
(immunology)
- Dermatitis, Allergic Contact
(diagnosis, etiology)
- Dermatitis, Occupational
(diagnosis, etiology)
- Female
- Humans
- India
- Lactones
(immunology)
- Male
- Middle Aged
- Patch Tests
- Plants
(adverse effects, immunology)
- Sesquiterpenes
(immunology)
- Tanacetum
(immunology)
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