A major cause of
female infertility is fallopian tube obstruction and traditional conservative and interventional treatments have been largely unsuccessful, especially in patients with distal
tubal obstruction. The objective of the current study was to compare the curative outcome of
ozone (treatment group) and conventional interventional treatment (comparison group) through comparing the different effects in the
infertility cases caused by fallopian tube obstruction, with the purpose to provide future reference for better treatment regimen for
tubal obstruction. 400 infertile cases caused by
tubal obstruction admitted in the Second Affiliated Hospital of Shaanxi University of Chinese Medicine from August 2006 to January 2012 were enrolled in this study and received either
ozone or conventional interventional treatment. No difference was observed between post-operative proximal tube recanalization rates in the two groups; however, post-operative distal tube recanalization rate and recanalization rate after 6 months were significantly higher in the treatment group. Importantly, the adhesion and conception rates were significantly lower and higher, respectively, in the treatment group compared to the comparison group after six months. Hence,
ozone therapy can potentially become a viable treatment modality for far-end
tubal obstruction patients.