A study of the efficacy and safety of albendazole (Zentel) in the treatment of intestinal helmenthiasis in Kenyan children less than 2 years of age.

Abstract

One hundred children comprising of 57 males and 43 females aged between 8 and 24 months entered the study. 46 children had single and 54 children had multiple helminth infections. All children received albendazole 200 mg (10 ml) suspension as a single dose. Albendazole proved very effective and safe in the treatment of single and multiple helminth infections in children under 2 years of age, achieving cure rates of 100% in both Ascaris lumbricoides and Necator americanus respectively, 83% in Trichuris trichiura and 66% in Hymenolepis nana. Treatment of polyparasitism appears to be of benefit in improving nutritional status using haemoglobin concentrations as an index.

• Authors: H O Pamba, N O Bwibo, C N Chunge, B B Estambale
• Journal: East African medical journal (East Afr Med J) Vol. 66 Issue 3 Pg. 197-202 (Mar 1989) ISSN: 0012-835X [Print] Kenya
• PMID: 2591328 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Albendazole

Topics

• Albendazole (therapeutic use)
• Female
• Helminthiasis (drug therapy)
• Humans
• Infant
• Male