Abstract |
In less than two decades, activity-based protein profiling (ABPP) has expanded to become the de facto tool for the study of small molecule- protein interactions in a proteomic environment. In this issue, Na et al. (2015) present another ABPP method, which they called reactive probe-based chemical proteomics, to study host-pathogen interaction and subsequently identify the protein PheA as a potential key effector during the pathogen infection process.
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Authors | Jingyan Ge, Shao Q Yao |
Journal | Chemistry & biology
(Chem Biol)
Vol. 22
Issue 4
Pg. 434-435
(Apr 23 2015)
ISSN: 1879-1301 [Electronic] United States |
PMID | 25910239
(Publication Type: Journal Article, Comment)
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Copyright | Copyright © 2015 Elsevier Ltd. All rights reserved. |
Chemical References |
- Bacterial Proteins
- Prephenate Dehydratase
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Topics |
- Animals
- Bacterial Proteins
(metabolism)
- Host-Pathogen Interactions
- Prephenate Dehydratase
(metabolism)
- Proteomics
- Salmonella Infections
(microbiology)
- Salmonella typhimurium
(physiology)
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