Abstract | OBJECTIVES: The aim of this study was to determine the effects of intraoperative hyperglycemia on postoperative outcomes in orthotopic liver transplant recipients. MATERIALS AND METHODS: After ethics committee approval was obtained, we retrospectively analyzed the records of patients who underwent orthotopic liver transplant from January 2000 to December 2013. A total 389 orthotopic liver transplants were performed in our center, but patients aged < 15 years (179 patients) were not included in the analyses. Patients were divided into 2 groups based on their maximum intraoperative blood glucose level: group 1 (patients with intraoperative blood glucose level < 200 mg/dL) and group 2 (patients with intraoperative blood glucose level > 200 mg/dL). Postoperative complications between the 2 groups were compared. RESULTS: There were 58 patients (37.6%; group 1, blood glucose < 200 mg/dL) who had controlled blood glucose and 96 patients (62.3%; group 2, blood glucose > 200 mg/dL) who had uncontrolled blood glucose. The mean age and weight for groups 1 and 2 were similar. There were no differences between the 2 groups regarding the duration of anhepatic phase (P = .20), operation time (P = .41), frequency of immediate intraoperative extubation (P = .14), and postoperative duration of mechanical ventilation (P = .06). There were no significant differences in frequency of patients who had postoperative infectious complications, acute kidney injury, or need for hemodialysis. Mortality rates after liver transplant were similar between the 2 groups (P = .81). CONCLUSIONS:
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Authors | Özgür Kömürcü, Aynur Camkıran Fırat, Şerife Kaplan, Adnan Torgay, Arash Pirat, Mehmet Haberal, Gülnaz Arslan |
Journal | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
(Exp Clin Transplant)
Vol. 13 Suppl 1
Pg. 335-9
(Apr 2015)
ISSN: 2146-8427 [Electronic] Turkey |
PMID | 25894186
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Biomarkers
(blood)
- Blood Glucose
(metabolism)
- Female
- Humans
- Hyperglycemia
(blood, diagnosis, etiology, mortality)
- Intraoperative Period
- Liver Transplantation
(adverse effects, mortality)
- Male
- Middle Aged
- Operative Time
- Postoperative Complications
(mortality, therapy)
- Respiration, Artificial
- Retrospective Studies
- Risk Factors
- Time Factors
- Treatment Outcome
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