Abstract |
Angiomyomatous hamartoma (AMH) is a rare benign lesion, which occurs almost exclusively in the inguinal lymph nodes. We herein report a case of a female elder who presented with a long-standing inguinal mass. Microscopically, the mass showed a zonal distribution, characterized by thick-walled muscular vessels, fibrosis, and calcification in the hilum and proliferating spindle cells around thin-walled vessels and plexiform vessel tangles at the periphery. The spindle cells show positive immunoreactivity of smooth muscle actin and CD34 with a heterogeneous expression of desmin and CD44. Although the pathogenesis of AMH remains uncertain, the histological features and immunohistochemical findings of this case imply a disordered or exuberant angiogenic process.
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Authors | Chii-Hong Lee, Tung-Cheng Chang, Jan-Wen Ku |
Journal | Indian journal of pathology & microbiology
(Indian J Pathol Microbiol)
2015 Apr-Jun
Vol. 58
Issue 2
Pg. 226-8
ISSN: 0974-5130 [Electronic] India |
PMID | 25885141
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antigens, CD34
- Biomarkers, Tumor
- CD44 protein, human
- Desmin
- Hyaluronan Receptors
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Topics |
- Aged, 80 and over
- Antigens, CD34
(analysis)
- Biomarkers, Tumor
(analysis)
- Calcinosis
- Desmin
(analysis)
- Female
- Fibrosis
- Hamartoma
(diagnosis, pathology)
- Histocytochemistry
- Humans
- Hyaluronan Receptors
(analysis)
- Immunohistochemistry
- Lymph Nodes
(pathology)
- Microscopy
- Muscle Cells
(pathology)
- Pericytes
(pathology)
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