Abstract | OBJECTIVE: METHODS: Seventy-two OP patients in our hospital were selected as an OP group, and another 72 healthy subjects were used as a control group. Their BGP, B-ALP and CTX levels as well as bone mineral density (BMD) values were measured. The correlations between BGP, B-ALP and CTX levels and BMD values were determined. RESULTS: The BGP level of the OP group [(5.61±5.52) ng/ml] was significantly higher than that of the control group (P<0.05), but the levels of B-ALP and CTX did not differ significantly (P>0.05). The BMD values of femoral neck and Ward's triangle in the OP group were negatively correlated with the B-ALP levels (P<0.05). For women OP patients, the BMD values of femoral neck and Ward's triangle were also negatively correlated with the B-ALP levels (P<0.05). The BMD of femoral neck in the control group was negatively correlated with the CTX level (P<0.05). CONCLUSION: Determining BGP, B-ALP and CTX levels can evaluate the bone metabolism degree, which provides evidence for clinical typing of OP and developing treatment strategies.
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Authors | Dongfeng Zhao, Junsheng Wang, Yining Liu, Xinwei Liu |
Journal | Pakistan journal of medical sciences
(Pak J Med Sci)
2015 Jan-Feb
Vol. 31
Issue 1
Pg. 91-4
ISSN: 1682-024X [Print] Pakistan |
PMID | 25878621
(Publication Type: Journal Article)
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