Therapy of corneal erosions and 'dry eye' with Solcoseryl and Vitasic eye drops.

Abstract

A comparative study of Solcoseryl eye drops versus Vitasic eye drops has been carried out under controlled conditions (randomized and double-blind) on a total of 94 patients. 52 had corneal erosion, 30 had dry eye syndrome, 8 cases could not be evaluated. In addition, 2 eyes with photophthalmia were treated with Vitasic and 2 showing keratitis with Solcoseryl. There were no adverse reactions other than 2 instances of stinging with Solcoseryl and 1 case of severe irritation after Vitasic. The patients were examined on days 0, 1, 3 and 7. Results showed a consistent superiority of Solcoseryl eye drops in respect to speed of healing of corneal erosions and moistening of the cornea in the 'dry eye' syndrome which reached statistical significance in some parameters.

• Authors: H M Krannig, H Rohde-Germann, W Straub
• Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde (Ophthalmologica) Vol. 199 Issue 2-3 Pg. 100-5 ( 1989) ISSN: 0030-3755 [Print] Switzerland
• PMID: 2587017 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Nucleosides
• Nucleotides
• Ophthalmic Solutions
• Tissue Extracts
• Vitasic
• Actihaemyl

Topics

• Actihaemyl (therapeutic use)
• Corneal Diseases (drug therapy, etiology)
• Double-Blind Method
• Dry Eye Syndromes (drug therapy)
• Eye Foreign Bodies (complications)
• Humans
• Nucleosides (therapeutic use)
• Nucleotides (therapeutic use)
• Ophthalmic Solutions
• Prognosis
• Random Allocation
• Tears (metabolism)
• Tissue Extracts (therapeutic use)
• Wound Healing (drug effects)