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[Pneumomediastinum and cutaneous necrosis in dermatomyositis: Report of one case].

Abstract
We report a 37 years old male with a dermatomyositis treated with oral cyclophosphamide. He was admitted to the hospital due to a zone of skin necrosis with purulent exudate, located in the second left toe. A complete blood count showed a leukocyte count of 2,600 cells/mm³. A Chest CAT scan showed a pneumomediastinum with emphysema of adjacent soft tissue. Cyclophosphamide was discontinued and leukocyte count improved. The affected toe was amputated and a chest CAT scan showed a partial resolution of the pneumomediastinum. We discuss and review the pathogenesis, clinical presentation and management of pneumomediastinum and cutaneous necrosis in association with dermatomyositis.
AuthorsNatalia Gallardo C, Omar Valenzuela L, Sebastián Ibáñez V
JournalRevista medica de Chile (Rev Med Chil) Vol. 143 Issue 1 Pg. 120-3 (Jan 2015) ISSN: 0717-6163 [Electronic] Chile
Vernacular TitleNeumomediastino y necrosis cutánea en asociación a dermatomiositis: presentación de un caso clínico y revisión de la literatura.
PMID25860279 (Publication Type: Case Reports, English Abstract, Journal Article, Review)
Topics
  • Adult
  • Amputation, Surgical
  • Dermatomyositis (complications, therapy)
  • Humans
  • Male
  • Mediastinal Emphysema (etiology, therapy)
  • Necrosis (pathology)
  • Skin (pathology)

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