[Detection of gingipain K in the gingival crevicular fluid of orthodontic patients].

Abstract

PURPOSE:

To explore the correlation between gingipain K (Kgp) and inflammatory reaction of gum in the process of orthodontic treatment, and analyse the role of Kgp in the development of gingivitis during orthodontic treatment.

METHODS:

Totally 45 orthodontic healthy teenagers were randomly chosen for the study. The subgingival plaques were collected simultaneously before orthodontic treatment and 3 months after treatment. 16S rDNA PCR technique was used to detect Porphyromonas gingivalis (P.g) and Kgp. SPSS17.0 software package was used for statistical analysis.

RESULTS:

The detection rate of Kgp was 35.71% before orthodontic treatment and 67.86% after treatment. Positive correlation (P<0.05) was observed between Kgp and gingival inflammation.

CONCLUSIONS:

Fixed orthodontic appliances cause plaque accumulation, accordingly slight gingiva inflammation and the increament of P.gingivalis in the early stage.

• Authors: Gang-Ling Yang, Wei-Zhe Li, Zhi-Qiang Han, Shui-Qing Xiao
• Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology (Shanghai Kou Qiang Yi Xue) Vol. 24 Issue 1 Pg. 102-6 (Feb 2015) ISSN: 1006-7248 [Print] China
• PMID: 25858379 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Adhesins, Bacterial
• Gingipain Cysteine Endopeptidases
• Cysteine Endopeptidases

Topics

• Adhesins, Bacterial
• Adolescent
• Cysteine Endopeptidases
• Dental Plaque
• Gingipain Cysteine Endopeptidases
• Gingiva
• Gingival Crevicular Fluid
• Gingivitis
• Humans
• Orthodontic Appliances
• Porphyromonas gingivalis