Abstract | BACKGROUND AND OBJECTIVE: PATIENTS AND METHODS: A retrospective review of all patients at the Cole Eye Institute who received anti- VEGF injections for exudative AMD and underwent optical coherence tomography (OCT) evaluation was performed. A total of 543 patients were identified and included in the study. The number of treatments and the change in Snellen visual acuity from the time of diagnosis until the development of ORT were tabulated. RESULTS: Seventy individuals with ORT were identified. The data analyzed showed a wide variation in the number of treatments until the development of ORT and did not show a significant correlation between ORT incidence and decreased visual acuity. CONCLUSION: Although a correlation was found between the increased incidence of ORT and length of anti- VEGF treatment, there was no evidence of decreased visual acuity, which suggests that the ORT might be benign.
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Authors | Juliana R Gildener-Leapman, Sunil Srivistava, Justis P Ehlers, Peter K Kaiser |
Journal | Ophthalmic surgery, lasers & imaging retina
(Ophthalmic Surg Lasers Imaging Retina)
Vol. 46
Issue 3
Pg. 345-8
(Mar 2015)
ISSN: 2325-8179 [Electronic] United States |
PMID | 25856821
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright 2015, SLACK Incorporated. |
Chemical References |
- Angiogenesis Inhibitors
- VEGFA protein, human
- Vascular Endothelial Growth Factor A
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Topics |
- Angiogenesis Inhibitors
(administration & dosage, therapeutic use)
- Humans
- Intravitreal Injections
- Prevalence
- Retina
(pathology)
- Retreatment
- Retrospective Studies
- Tomography, Optical Coherence
- Vascular Endothelial Growth Factor A
(antagonists & inhibitors)
- Visual Acuity
(physiology)
- Wet Macular Degeneration
(drug therapy, physiopathology)
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