Comparison of Lotrafilcon B and Balafilcon A silicone hydrogel bandage contact lenses in reducing pain and discomfort after photorefractive keratectomy: A contralateral eye study.

Abstract

PURPOSE:

To assess the effect of two silicone hydrogel contact lenses with high oxygen permeability in patients having photorefractive keratectomy (PRK).

SETTING:

Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

METHODS:

Sixty patients (120 eyes) who had bilateral PRK were enrolled in this double blind clinical trial. Each patient was fitted with a Lotrafilcon B (Air Optix(®)AQUA, Ciba Vision, Duluth, GA, USA) lens in one eye and a Balafilcon A (PureVision™ Bausch & Lomb, Rochester, NY, USA) lens in the fellow eye. Patients' responses to a subjective questionnaire in terms of pain, foreign body sensation, photophobia, blurred vision and epiphora were evaluated on the first and third postoperative days.

RESULTS:

Mean pain score for Lotrafilcon B and Balafilcon A contact lenses was 4.43±3.18 vs. 5.45±3.37 on the first postoperative day and 3.43±3.23 vs. 3.88±3.01 on the third postoperative day. However, the difference was only significant in the first 24h after surgery (P=0.032). Foreign body sensation was clinically higher with Balafilcon A contact lens (5.0±3.47 vs. 4.08±3.34 on day 1 and 4.98±3.52 vs. 3.55±3.20 on day 3) and the difference was statistically significant on the first and the third postoperative days (P=0.042 and 0.002, respectively). There was no statistically significant difference between two contact lenses in terms of photophobia, epiphora and blurred vision (P>0.05).

CONCLUSION:

The Lotrafilcon B lens resulted in significantly less postoperative pain and discomfort after PRK, especially in the first 24h after PRK.

• Authors: Mehrdad Mohammadpour, Afsaneh Amouzegar, Hassan Hashemi, Mahmoud Jabbarvand, Hamed Kordbacheh, Firoozeh Rahimi, Mohammad Naser Hashemian
• Journal: Contact lens & anterior eye : the journal of the British Contact Lens Association (Cont Lens Anterior Eye) Vol. 38 Issue 3 Pg. 211-4 (Jun 2015) ISSN: 1476-5411 [Electronic] England
• PMID: 25843674 (Publication Type: Journal Article, Randomized Controlled Trial)
• Copyright: Copyright © 2015. Published by Elsevier Ltd.

Chemical References

• Hydrogels
• Silicones
• balafilcon A
• lotrafilcon B

Topics

• Adolescent
• Adult
• Bandages, Hydrocolloid
• Contact Lenses, Hydrophilic
• Double-Blind Method
• Female
• Follow-Up Studies
• Humans
• Hydrogels (administration & dosage)
• Male
• Middle Aged
• Myopia (surgery)
• Pain, Postoperative (drug therapy)
• Photorefractive Keratectomy (adverse effects, methods)
• Retrospective Studies
• Silicones (administration & dosage)
• Young Adult