Abstract | BACKGROUND: MATERIALS AND METHODS: Sixty patients undergoing elective nonophthalmic surgery under general anesthesia were included in this clinical study. Patients were randomly assigned into three groups to receive 0.5 mcg/kg dexmedetomidine (Group D), 2 mcg/kg clonidine (Group C) or normal saline (Group S) as premedication i.v. over a period of 10 min before induction. IOP, heart rate, and mean arterial pressure were recorded before and after premedication, after suxamethonium, after intubation and then after 5 min. RESULTS: Following administration of dexmedetomidine and clonidine IOP decreased in both groups. After suxamethonium IOP increased in all three groups but it never crossed the baseline in Group D and C. After laryngoscopy and intubation IOP again increased in all three groups but in dexmedetomidine group it never crossed the baseline whereas in clonidine group it was significantly higher than the baseline. CONCLUSION:
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Authors | Puneet K Banga, Dhananjay K Singh, Shalini Dadu, Meenakshi Singh |
Journal | Saudi journal of anaesthesia
(Saudi J Anaesth)
2015 Apr-Jun
Vol. 9
Issue 2
Pg. 179-83
ISSN: 1658-354X [Print] India |
PMID | 25829907
(Publication Type: Journal Article)
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