Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization.

Abstract

Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a large hemoperitoneum after receiving Cefazolin antibiotic prophylaxis for a transvaginal oocyte retrieval. The patient was admitted to the intensive care unit for resuscitation with blood products. The presence of drug-dependent platelet antibodies to Cefazolin was confirmed serologically.

• Authors: Ioanna A Comstock, Michelle Longmire, Richard H Aster, Amin A Milki
• Journal: Case reports in obstetrics and gynecology (Case Rep Obstet Gynecol) Vol. 2015 Pg. 890610 ( 2015) ISSN: 2090-6684 [Print] United States
• PMID: 25810935 (Publication Type: Journal Article)